NPWT (Negative Pressure Wound Therapy) applies a localized vacuum to help the healing of the wound while stimulating granulation tissue formation and removing exudate.
There are five main mechanisms by which the application of negative pressure to a wound may aid in the healing process: Wound retraction Stimulation of granulation tissue formation Continuous removal of exudate Continuous wound cleansing Reduction of interstitial edema
Indications for Use NPWT can be applied to various types of wounds:  Diabetic ulcers  Pressure ulcers  Vascular ulcers (includes venous ulcers and arterial ulcers)  Burn wounds  Surgical wounds  Trauma–induced wounds Contraindications:  Exposed vasculature, nerves, anastomotic site, or organs.  Necrotic tissue with eschar present.  Untreated osteomyelitis.  Non–enteric and unexplored fistulas.  Malignancy in the wound bed.